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Management of Gastroesophageal Reflux Disease (GERD)


Management of Gastroesophageal Reflux Disease (GERD)

The first line options available for the management of gastroesophageal reflux disease are lifestyle modifications. However, usually they are not enough and the patient requires the addition of other medications for the effective treatment of GERD.

The medications currently used for the treatment of GERD include proton pump inhibitors, H2-receptor antagonist, antacids and Prokinetic drugs.

Proton Pump Inhibitors

Proton pump inhibitors constitute a class of drugs that are considered the most powerful agents currently available for the treatment of GERD. They include medications such as Omeprazole, Esomeprazole, Lansoprazole, and Pantoprazole. There are numerous studies available to support the use of Proton pump inhibitors as number one therapeutic agents for the treatment of GERD as is obvious from the following examples.

An experimental study was conducted to assess the efficiency of a Proton pump inhibitor called Omeprazole for the treatment of GERD patients. They were divided into two groups. The patients in one group received a low dose of Omeprazole and the patient in the other group received a high dose of Omeprazole. This therapy was continued for about 4 week’s time. At the end of treatment, it was observed that about 31% of patients treated with a low dose of Omeprazole and 40% of the patients treated with a high dose were symptoms free. In a similar study, it was reported that the use of Esomeprazole decreases the night time symptoms associated with GERD.

Proton pump inhibitors are usually safe drugs. The serious side effects noted with the use of PPIs although rare include:

A decrease in calcium absorption:

Calcium is of critical importance for the growth of bones. This is why by decreasing the absorption of Calcium long-term use of proton pump inhibitors can make the bones weak and increase the chances of fractures.

Increased risk of infections:

The acid in the stomach can protect us against infection by killing the causative microorganisms. Thus by decreasing the production of acid in the stomach PPIs can decrease the risk of certain infections.

Read more info: https://www.centurymedicaldental.com/management-of-gastroesophageal-reflux-disease-gerd/ 

Century Medical & Dental Center

200 Livingston Street,

Brooklyn, NY 11201

(718) 522-3399

https://www.centurymedicaldental.com

Century Medical & Dental Center

770 Flatbush Ave,

Brooklyn, NY 11226

(347) 627-3988

https://www.centurymedicaldental.com

Century Medical & Dental Center

260 Ave X,

Brooklyn, NY 11223

(718) 336-8855

https://www.centurymedicaldental.com


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